| Lucie Arnaz | Muriel | (May 23, 2006-Sep 3, 2006) |
| Jacqueline Bayne | Ensemble | |
| Keith Carradine | Lawrence | (Jul 21, 2006-Sep 3, 2006) |
| Rachel deBenedet | Lenore | |
| Rene | ||
| Muriel | (May 2, 2006-May 21, 2006) | |
| Will Erat | Ensemble | |
| Tom Galantich | Hotel Manager | |
| Nikos | ||
| Sara Gettelfinger | Jolene | (May 2, 2006-Sep 3, 2006) |
| Joan Hess | Ensemble | |
| Sophia | ||
| Mylinda Hull | Jolene | (Jan 17, 2006-Apr 30, 2006) |
| Brian d'Arcy James | Freddy | (Jul 21, 2006-Sep 3, 2006) |
| Richard Kind | Andre | (Aug 3, 2006-Sep 3, 2006) |
| Jonathan Pryce | Lawrence | (Jan 17, 2006-Jul 16, 2006) |
| Chuck Saculla | Ensemble | |
| Sherie Rene Scott | Christine | (Jun 20, 2006-Sep 3, 2006) |
| Timothy Edward Smith | Swing | |
| Dennis Stowe | Ensemble | |
| Matt Wall | Ensemble | |
| Rachel York | Christine | (Feb 5, 2006-Jun 19, 2006) |