| ACT 1 | Sung By |
| Karma | Orchestra |
| Night of Screams | Sailor, John Blackthorne (an English sea captain of the Erasmus) and Ensemble |
| This is Samurai | Samurai |
| How Nice to See You | Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan), Lord Buntaro (Daimyo of Anjiro Province, married to Lady Mariko), Father Alvito (a Portugese priest) and Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Impossible Eyes | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| He Let Me Live | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Honto | John Blackthorne (an English sea captain of the Erasmus) |
| Assassination | Father Alvito (a Portugese priest) and Captain General Ferriera (Portugese Captain of the Black Ship) |
| Shogun | Hostages |
| Royal Blood | Lord Ishido (the most powerful Daimyo in Japan) and Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan) |
| An Island | Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan) |
| No Word for Love | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Mad Rum Below/Escape | John Blackthorne (an English sea captain of the Erasmus) and Ensemble |
| Karma | Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan) and Ensemble |
| Born to Be Together | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| ACT 2 | Sung By |
| Fireflies | Ensemble, Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| Sail Home | John Blackthorne (an English sea captain of the Erasmus) |
| Rum Below | John Blackthorne (an English sea captain of the Erasmus), Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan) and Ensemble |
| Pillowing | Gyoko (Madam of the Tea House, owner of Kiku's contract), Kiku (courtesan of the first class) and Ladies |
| Born to Be Together (Reprise) | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| No Man | John Blackthorne (an English sea captain of the Erasmus) |
| Cha-No -Yu | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and Lord Buntaro (Daimyo of Anjiro Province, married to Lady Mariko) |
| Absolution | Father Alvito (a Portugese priest), An Acolyte, Ensemble and Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Poetry Competition | Lord Ishido (the most powerful Daimyo in Japan), Sazuko (Toranaga's youngest consort) and Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Death Walk | Ensemble and John Blackthorne (an English sea captain of the Erasmus) |
| One Candle | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| Ninja Raid | Orchestra |
| One Candle (Reprise) | Lady Mariko (educated by the Jesuits, married to Lord Buntaro) and John Blackthorne (an English sea captain of the Erasmus) |
| Winter Battle | Orchestra |
| Resolutions | Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan) and Ensemble |
| Trio | Lord Toranaga (Overlord of Central Province, 2nd most powerful Daimyo in Japan), John Blackthorne (an English sea captain of the Erasmus) and Lady Mariko (educated by the Jesuits, married to Lord Buntaro) |
| Finale | Ensemble |